---
title: "On-Demand Webinar: Historical Control Database of Neoplastic and Non-neoplastic Lesions in 6 month Tg.rasH2 Studies"
description: In this exclusive webinar, we will explore the historical control database of neoplastic & non-neoplastic lesions from dozens of rasH2 carcinogenicity studies.
---

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# ON-DEMAND WEBINAR Historical Control Database of Neoplastic and Non-neoplastic Lesions in 6 month Tg.rasH2 Studies

Presented by:

### Madhav Paranjpe, DVM, MS, PhD, DACVP, FIATP Director of Pathology at BioReliance

 The **[rasH2 transgenic mouse](https://www.taconic.com/transgenic-mouse-model/rash2)** supports faster and more accurate carcinogenicity studies, with 75% shorter timelines than conventional two-year rodent bioassays. Can this transgenic mouse tighten your drug development pipeline, while reducing false positives?

## Carcinogenicity Testing Insights

![1178-rash2-insight.jpg](https://info.taconic.com/hs-fs/hubfs/social-suggested-images/1178-rash2-insight.jpg?width=300&name=1178-rash2-insight.jpg "Webinar: Historical Control Database of Neoplastic and Non-neoplastic Lesions in 6 month Tg.rasH2 Studies") In this exclusive webinar, we will explore the historical control database of neoplastic and non-neoplastic lesions from dozens of rasH2 carcinogenicity studies, demonstrating an extremely low incidence of the spontaneous tumors and non-lethal legions which can confound two-year rodent carcinogenicity studies.

- Low incidence of spontaneous tumors
- No tumor drifts
- Low incidence of lethal degenerative changes
- 75% shorter carcinogenicity testing studies

## Presenter:

![Dr. Madhav Paranjpe](https://info.taconic.com/hs-fs/hubfs/images/landing-pages/dr-madhav-paranjpe-photo.jpg?width=176&name=dr-madhav-paranjpe-photo.jpg "Dr. Madhav Paranjpe") Dr. Madhav Paranjpe, DVM, MS, PhD, DACVP, FIATP, is a Director of Pathology at BioReliance in Rockville, MD, USA. He is primarily involved in the evaluation of Dose Range Finding Studies and final six-month short term carcinogenicity studies.

 Dr. Paranjpe has published twenty papers in peer-reviewed journals and presented several seminars on transgenic mice, particularly the **[Tg.rasH2](https://www.taconic.com/transgenic-mouse-model/rash2)**. He received an Best Publication award in 2013 from ACT/IJT. Recently, in 2016, he received an award from the 2016 IQ Consortium and AAALAC International Global 3Rs Award for North America for his paper. “Regulatory Forum Opinion Piece\*: Retrospective Evaluation of Doses in the 26-week **[Tg.rasH2](https://www.taconic.com/transgenic-mouse-model/rash2)** Mice Carcinogenicity Studies: Recommendation to Eliminate High Doses at Maximum Tolerated Dose (MTD) in Future Studies.”

## View this exclusive webinar!

### Watch Now!

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