---
title: "On-Demand Webinar: Discover huNOG-EXL - Extending the Limits of Engrafted Human Immune System Models"
description: Learn more about engrafted human immune models and their impact for allergy, inflammation and immune-oncology research.
---

[![Taconic Biosciences - huNOG-EXL mouse model](https://info.taconic.com/hs-fs/hubfs/Taconic%20Biosciences_New%20Logo-1.png?width=400&height=83&name=Taconic%20Biosciences_New%20Logo-1.png "Taconic Biosciences - huNOG-EXL mouse model")](http://www.taconic.com/mouse-model/hunog-exl)

# ON-DEMAND WEBINAR Discover huNOG-EXL: Extending the Limits of Engrafted Human Immune System Models

Presented by  
**Dr. Michael Seiler**

![Webinar: Discover huNOG-EXL](https://info.taconic.com/hs-fs/hubfs/images/hunog-exl-webinar-icon.jpg?width=300&name=hunog-exl-webinar-icon.jpg "Webinar: Discover huNOG-EXL")

Taconic Biosciences’ Dr. Michael Seiler, Associate Director, Genetically Engineered Models Design and Precision Research Models, presented an e-seminar featuring some of the latest applications of Taconic’s newest extended lineage NOG model, **[huNOG-EXL](http://www.taconic.com/mouse-model/hunog-exl)**, designed for applications in allergy, inflammation and immuno-oncology research.

Learn more about engrafted human immune models and their impact for allergy, inflammation and immuno-oncology research.

### Mimicking Human Immune Responses

The development of animal models capable of mimicking human immune responses is crucial to study the pathophysiology of disease and to generate new therapeutic methodologies. Significant advances in immunology modeling have been made utilizing the super immune-deficient CIEA NOG mouse®, but the full application of engrafted human immune models depends upon overcoming some cross-species differences.

### Key Learning Points:

This webinar provided insights on the current state of immune system engraftment and additional information on:

- Methodologies and best practices employed for immune system engraftment
- Strengths and limitations of current human immune system engraftment technologies and the latest products providing innovative solutions
- Applications of huNOG-EXL™ human immune system models in allergy, inflammation, and immuno-oncology
- Biological underpinnings of hematopoietic lineage commitment in NOG and NOG-EXL mice

### Watch Now!

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