Webinar: Cre-Luc GPCR Report Mouse Platform
Presented by
Mr. Greg Polites

The CRE-Luc GPCR Reporter Mouse Platform is an in vitro/in vivo luciferase reporter platform for profiling of leads in GPCR drug development. How can this platform provide utility in development of GPCR targeting drugs? This webinar will provide you with a thorough understanding of the practical applications for the CRE-Luc GPCR reporter mouse model platform and insights into how it can be utilized to accelerate your research.

Key Learning Points:

  • The CRE-Luc model GPCR mouse model - from its conception through the initial applications

  • The potential of this platform technology to rank small molecule leads at an early part of their development and accelerate their advancement to more complicated animal disease models

  • Data generated using both established and experimental compounds in demonstrating a new paradigm of applying High Throughput Screening (HTS) assays to mechanistic animal models

  • Experiments that demonstrate the ability to track receptor activity of Gi, Gs and Gq GPCR receptors via whole animal imaging, in tissue sections, and in isolated primary cells

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© 2021 Taconic Biosciences, Inc. All rights reserved.

© 2021 Taconic Biosciences, Inc. All rights reserved.