ON-DEMAND WEBINAR The CRE-Luc GPCR Reporter Mouse Platform - A New Paradigm to Accelerate Small Molecule Leads Toward in vivo Disease

The CRE-Luc GPCR Reporter Mouse Platform is an in vitro/in vivo luciferase reporter platform for profiling of leads in GPCR drug development. How can this platform provide utility in development of GPCR targeting drugs? This webinar will provide you with a thorough understanding of the practical applications for the CRE-Luc GPCR reporter mouse model platform and insights into how it can be utilized to accelerate your research.

Key Learning Points:

• The CRE-Luc model GPCR mouse model - from its conception through the initial applications
  
  
• The potential of this platform technology to rank small molecule leads at an early part of their development and accelerate their advancement to more complicated animal disease models
  
  
• Data generated using both established and experimental compounds in demonstrating a new paradigm of applying High Throughput Screening (HTS) assays to mechanistic animal models
  
  
• Experiments that demonstrate the ability to track receptor activity of G_i, G_s and G_q GPCR receptors via whole animal imaging, in tissue sections, and in isolated primary cells