huNOG-constitutive-knockout-mouse-modelModeling the tumor microenvironment in a clinically translatable way requires an active, representative human immune system.

hIL-6 NOG mice demonstrate enhanced differentiation into human monocytes/macrophages after hematopoietic stem cell engraftment, making them a promising tool for exploring immuno-therapy candidates targeting tumor-associated macrophages.

Tumor Associated Macrophages in Humanized hIL-6 NOG

In this free webinar presented by Taconic Biosciences and Dr. Takeshi Takahashi, you'll learn about modeling the tumor microenvironment with hIL-6 NOG humanized mice.

Webinar Takeaways

  • Learn how the hIL-6 NOG recapitulates human hematopoiesis

  • Explore the uses of humanized models in immuno-oncology drug discovery

  • Discover new ways of studying regulatory myeloid cells with hIL-6 NOG mice


Dr. Takeshi Takahashi from the CIEA InstituteDr. Takeshi Takahashi is head of the Immunology Lab at the Central Institute for Experimental Animals (CIEA) in Kawasaki, Japan. He completed his PhD at Osaka University and spent seven years studying regulatory T cells at Kyoto University with Prof. Sakaguchi.

After working with Stanford University and DRFZ as a visiting scientist, Dr. Takeshi Takahashi began researching humanized mice at Tohoku University and joined the CIEA in 2011. He has published thirty peer-reviewed papers in the field of immunology.


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© 2024 Taconic Biosciences, Inc. All rights reserved.

© 2024 Taconic Biosciences, Inc. All rights reserved.