PDX Webinar Presented by
Els Hermans, DVM - University of Leuven

Patient-derived tumor xenograft (PDX) models are established from the immediate transfer of fresh human tumor tissue in immunocompromised mice and further propagated into successive generations (F1, F2, F3, etc). Despite these serial passages, the intra-tumor heterogeneity and histologic characteristics are maintained and, consequently, a better retention of the morphological and molecular markers of the primary tumors is reached.

Key Learning Points:

  • Discussion on how patient-derived xenograft (PDX) models are established

  • Understand how PDX models are characterized and how those characteristics are maintained across successive passages

  • Discover why PDX models may be more relevant to translational studies

  • Learn how PDX models can be employed in basic research and to guide clinical research

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© 2022 Taconic Biosciences, Inc. All rights reserved.

© 2022 Taconic Biosciences, Inc. All rights reserved.