While the specialized immune systems of xenograft tumor models allow us to investigate specific human cancers, further progress in immuno-oncolgy depends on more representative modeling of the tumor microenvironment.Syngeneic tumor models, derived from cancer tissues of the same genetic background as their host, support experiments in the context of a complete and functional immune system.
Syngeneic Tumor Modeling:
In this webinar, Dr. Philip Dubé will introduce syngeneic tumor modeling and explore how it can be used to accelerate immuno-oncology research.Topics will include:
- The applications, advantages, and limitations of syngeneic tumor models.
- Pairing relevant tumor lines to pair with inbred rodent strains.
- Using genetically engineered animal models in syngeneic studies.
- Advanced applications for genetically humanized rodent models in immuno-oncology.
Presenter:
Dr. Philip Dubé is a Field Applications Scientist at Taconic Biosciences. He earned a PhD in Physiology and a Honors B.Sc. in Pharmacology from the University of Toronto and completed a postdoctoral fellowships at Vanderbilt University and Children’s Hospital Los Angeles.Dr. Dubé has over sixteen years of experience in the use of rodent models, with extensive knowledge of the application and execution of successful research studies.
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