Join us for our upcoming NASH Symposium!
Thursday, August 25th, 2022 from 11:00AM - 2:00PM ET/ 8:00AM - 11:00AM PT
Advancing NASH Research with Mice: Best Practices and Applications of Westernized Diets
11:00AM - 2:00PM ET | 8:00AM - 11:00AM PT
Nonalcoholic fatty liver disease (NAFLD) is a complex spectrum of disorders ranging from simple benign steatosis to steatohepatitis (NASH) with fibrosis. NAFLD is increasingly common around the world, especially in Western nations.
There are still no FDA-approved therapeutics for this metabolic disease due to extremely high attrition in late-phase clinical trials, making the selection of appropriate preclinical research models critical for drug approval.
Taconic Biosciences is bringing together researchers across academia and industry to discuss translational NASH modeling, particularly as embodied in Westernized diet through enrichment with fat, cholesterol, and fructose. Join us for this virtual event on Thursday, August 25, 2022 from 11:00AM-2:00PM ET/8:00AM-11:00AM PT.
This engaging workshop will examine the translational value of different approaches, immune involvement in NASH, and applications of the preclinical models toward discovery and development of targeted therapies.
We encourage you to pose questions and share your own experiences during this interactive event. There will be a brief Q&A segment following each speaking session, and the workshop will conclude with a roundtable discussion.
Complete the form to register for this upcoming workshop.
Workshop Agenda
11:00-11:10 AM | Welcome and Introduction to NASH Preclinical Modeling
Presented by Fred Beasley, PhD, Field Applications Scientist, Taconic Biosciences
11:10-11:35 AM | Dietary Considerations to Optimize NASH in Rodent Models
Presented by Sridhar Radhakrishnan, PhD, Senior Scientist, Research Diets, Inc
11:35-12:00 PM | Identification of Antigens in Diet Induced Nonalcoholic Steatohepatitis
Presented by Arion Kennedy, PhD, Assistant Professor, Department of Molecular and Structural Biochemistry, North Carolina State University
12:00-12:25 PM | Bioactive Lipids in NASH Pathogenesis
Presented by Harmeet Malhi, MBBS, Professor of Medicine and Physiology, Mayo Clinic
12:25-12:35PM | Break
12:35-1:20PM | Is There a Murine Model That Fully Recapitulates Human NASH? An Unbiased Bioinformatics Approach Proposed by the EU IMI2 LITMUS Consortium to Rank Pre-clinical Models Based on Proximity to Human Disease
Presented, on behalf of the EU-IMI2 LITMUS consortium and the University of Cambridge (UK), by Michele Vacca, MD, PhD, Assistant Professor at the University of Bari (IT) and Principal Investigator at the Roger Williams Institute of Hepatology (UK)
1:20-1:50PM | Panel Discussion
1:50-2:00PM | Closing Remarks
Presented by Fred Beasley, PhD, Field Applications Scientist, Taconic Biosciences
Register for the Workshop
Sridhar Radhakrishnan, PhD
Senior Scientist, Research Diets
Arion Kennedy, PhD
Assistant Professor, North Carolina State University
Harmeet Malhi, MBBS
Professor of Medicine and Physiology, Mayo Clinic
Michele Vacca, MD, PhD
Assistant Professor at the University of Bari (IT) and Principal Investigator at the Roger Williams Institute of Hepatology (UK), and member of the LITMUS European consortium
Fred Beasley, PhD
Field Applications Scientist, Taconic Biosciences