As drug discovery efforts rapidly shift towards increasingly complex and highly specific biologic therapeutics, sourcing appropriate in vivo models for preclinical work is becoming more challenging. Researchers are turning to humanized immune system (HIS) models for help addressing their in vivo drug research challenges.
Humanized Mouse Models for Drug Discovery
HIS mouse models have become invaluable tools for a multitude of research applications, ranging from immuno-oncology, autoimmune disease, infectious disease, to basic research into the immune system and hematopoiesis.
Discover how NOG mice can be utilized to accelerate preclinical research and drug discovery. This free white paper provides a thorough overview of HSC and PBMC engraftment models using the original NOG mouse, in addition to next generation models designed to support engraftment of particular human immune cell subsets, such as myeloid lineages and NK cells.
Read this white paper to:
.jpg)
