Attempts to capture the complexity of human cancer progression have been limited by models that fail to accurately recapitulate the disease.
Recent xenograft advances in utilizing immune deficient animal models, including genetically engineered mouse (GEM) models, have brought in vivo modeling into routine practice.
Using GEM Models for Mimicking Disease Progression
GEMs models have become indispensable for understanding tumor biology, enabling validation of in vitro findings, and mimicking critical elements of disease progression.
Download this White Paper to learn:
- The critical elements to in vivo study design, including model selection and expected outcomes
- The latest advances in utilizing spontaneous immune deficient mouse strains
- The application of Genetically Engineered Mouse (GEM) models in Oncology research programs
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