Xenograft Advances: Immune Deficient Animal Models
Attempts to capture the complexity of human cancer progression have been limited by models that fail to accurately recapitulate the disease.
Recent xenograft advances in utilizing immune deficient animal models, including genetically engineered mouse (GEM) models, have brought in vivo modeling into routine practice.
GEMs models have become indispensable for understanding tumor biology, enabling validation of in vitro findings, and mimicking critical elements of disease progression.
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